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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07024] Pipette Filler This protein and ATM share

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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07024] Pipette Filler This protein and ATM sharePDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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Description

This protein and ATM share similarity with Schizosaccharomyces pombe rad3| a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage

calcium-activated neutral proteases

Epigenetic silencing of this gene has been observed in gliomas

Translation of this protein is initiated at a non-AUG (AUA) start codon

This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1

PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07024] Pipette Filler This protein and ATM sharePDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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