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MAGC1 Polyclonal Antibody, 100ul Nucleic Acid Extraction Mutations in this gene impair

SKU: 39022040917

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MAGC1 Polyclonal Antibody, 100ul Nucleic Acid Extraction Mutations in this gene impairThis gene is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE homologous sequence, and therefore is about 800 aa longer than the other MAGE proteins.

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Description

Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections

exhibiting both depalmitoylating as well as lysophospholipase activity

KAP family members appear to have unique| family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur| the ultrahigh sulfur| and the high tyrosine/glycine KAPs

Multiple alternatively spliced variants of this gene| which encode distinct isoforms| have been reported

May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF

MAGC1 Polyclonal Antibody, 100ul Nucleic Acid Extraction Mutations in this gene impairThis gene is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE homologous sequence, and therefore is about 800 aa longer than the other MAGE proteins.

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