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PABP2 Polyclonal Antibody, 20ul Low retention tips Several alternatively spliced transcript variants

SKU: 39248124372

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PABP2 Polyclonal Antibody, 20ul Low retention tips Several alternatively spliced transcript variantsThis gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG

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Description

Several alternatively spliced transcript variants encoding different isoforms have been found for CD28

The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein

Alternatively spliced transcript variants encoding different isoforms have been characterized

The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer

This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer

PABP2 Polyclonal Antibody, 20ul Low retention tips Several alternatively spliced transcript variantsThis gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG

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