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APS Polyclonal Antibody, 100ul Recombinant Protein Expression Studies determined the encoded protein

SKU: 39726686330

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APS Polyclonal Antibody, 100ul Recombinant Protein Expression Studies determined the encoded proteinThe SH2B adaptor protein 2 encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc Grb2 pathway.

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Description

Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival

45 µm pore size and PES membrane

The protein encoded by this gene belongs to the lipid phosphate phosphatase (LPP) family

Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression

The protein encoded by EIF2AK3 (eukaryotic translation initiation factor 2 alpha kinase 3) phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2

APS Polyclonal Antibody, 100ul Recombinant Protein Expression Studies determined the encoded proteinThe SH2B adaptor protein 2 encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc Grb2 pathway.

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