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PDC10 Polyclonal Antibody, 50ul Digital Burette Existence of a major autoantigenic

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PDC10 Polyclonal Antibody, 50ul Digital Burette Existence of a major autoantigenicThis gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine threonine protein kinase MST4 to modulate the extracellular signal regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous

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Description

Existence of a major autoantigenic epitope or epitopes on the C-terminal 190 amino acids of p70 containing the leucine repeat

including Glanzmann thrombasthenia

IL20RA encodes a member of the type II cytokine receptor family

An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin

and could be potentially useful in cancer diagnosis

PDC10 Polyclonal Antibody, 50ul Digital Burette Existence of a major autoantigenicThis gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine threonine protein kinase MST4 to modulate the extracellular signal regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous

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