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Nox5 Polyclonal Antibody, 100ul Measuring Instruments The RGD motif is found

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Nox5 Polyclonal Antibody, 100ul Measuring Instruments The RGD motif is foundNOX5 (NADPH oxidase, EF hand calcium binding domain 5) is predominantly expressed in the testis and lymphocyte rich areas of spleen and lymph nodes. It encodes a calcium dependen NADPH oxidase that generates superoxide, and functions as a calcium dependent proton channel that may regulate redox dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for NOX5.

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Description

The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins

can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor

The protein is activated by heparin

Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD)

For more information on UNC5 proteins

Nox5 Polyclonal Antibody, 100ul Measuring Instruments The RGD motif is foundNOX5 (NADPH oxidase, EF hand calcium binding domain 5) is predominantly expressed in the testis and lymphocyte rich areas of spleen and lymph nodes. It encodes a calcium dependen NADPH oxidase that generates superoxide, and functions as a calcium dependent proton channel that may regulate redox dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for NOX5.

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