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AES Polyclonal Antibody, 50ul Buffer Solutions This gene encodes a member

SKU: 40639133003

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AES Polyclonal Antibody, 50ul Buffer Solutions This gene encodes a memberThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms

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Description

This gene encodes a member of the CHIC family of proteins

Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter

a transmembrane region and a highly conserved cytoplasmic tail

Mutations in this gene are associated with Turner type X-linked syndromic mental retardation

The chondroitin sulfate proteoglycan NG2 is a type I membrane protein expressed by subpopulations of glia including oligodendroglial precursor cells and a variety of tumor cells

AES Polyclonal Antibody, 50ul Buffer Solutions This gene encodes a memberThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms

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