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COL8A2 Polyclonal Antibody, 20ul Cryogenic Vials It is a secreted protein

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PLN111.00 PLN151.00

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COL8A2 Polyclonal Antibody, 20ul Cryogenic Vials It is a secreted proteinThis gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants.

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Description

It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway

3 bisphosphoglycerate (2

COL7A1 encodes the alpha chain of type VII collagen

Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome

Phosphorylates and activates not only PKB/AKT

COL8A2 Polyclonal Antibody, 20ul Cryogenic Vials It is a secreted proteinThis gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants.

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