FoxO3A Polyclonal Antibody, 100ul[BT-AP15669] General Lab Use Site-specific binding also suggests that

Site-specific binding also suggests that 53BP1 and 53BP2 are involved in p53-mediated tumor suppression

This protein may function as a transcriptional co-activator

This protein is located in the endoplasmic reticulum| and has been shown to possess ubiquitin ligase activity

Over 30 variant alleles have been identified which correlate with skin and hair color

May have a role in regeneration as well as neural plasticity in the adult nervous system

FoxO3A Polyclonal Antibody, 100ul[BT-AP15669] General Lab Use Site-specific binding also suggests thatThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.