Filamin 1(Phospho Ser2152) Polyclonal Antibody, 100ul Gloves It is predominantly expressed in

It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors

Low level of expression seen in the liver| thymus| and peripheral blood leukocytes

initiates the visual transduction cascade

or with the TAF15 gene on chromosome 17

The enzyme consists of two subunits

Filamin 1(Phospho Ser2152) Polyclonal Antibody, 100ul Gloves It is predominantly expressed inThe protein encoded by this gene is an actin binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias