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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07021] Organelle Studies and it initiates membrane penetration

SKU: 4167512196

4.3
SEK141.00 SEK168.00

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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07021] Organelle Studies and it initiates membrane penetrationPDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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Description

and it initiates membrane penetration of the complex

This is a paternally expressed imprinted gene that is thought to have been derived from the Ty3/Gypsy family of retrotransposons

Mutations in this gene cause Omenn syndrome

The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes

Alport syndrome with macrothrombocytopenia

PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07021] Organelle Studies and it initiates membrane penetrationPDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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