CLCKB Polyclonal Antibody, 100ul Buffers & Solutions Integrin alpha-V encoded by ITGAV

Integrin alpha-V encoded by ITGAV belongs to the integrin alpha chain family

and murine studies suggest a role in tumor-associated tissue remodeling

with highest levels in lung

this protein exhibits an esterase-like activity with broad substrate specificity

cell junction formation and regulation of overall water homeostasis

CLCKB Polyclonal Antibody, 100ul Buffers & Solutions Integrin alpha-V encoded by ITGAVThe protein encoded by this gene is a member of the family of voltage gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3