HIPK3 Polyclonal Antibody, 20ul Glassware Mitogen-activated protein kinase 8 encoded

Mitogen-activated protein kinase 8 encoded by MAPK8 is a member of the MAP kinase family

The L isoform is expressed only in hemopoietic cell lineages

|tissue specificity:Expressed in all adult human tissues| with 5-fold lower levels observed in the brain

The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85

tissue specificity:Predominantly expressed in brain and adrenal gland

HIPK3 Polyclonal Antibody, 20ul Glassware Mitogen-activated protein kinase 8 encodedCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors.,PTM: Autophosphorylated, but autophosphorylation is not required for Catalytic activity.,PTM: May be sumoylated.,Belongs to the protein kinase superfamily. CMGC Ser Thr protein kinase