CD11A Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation Mothers against decapentaplegic homolog 2

Mothers against decapentaplegic homolog 2 encoded by SMAD2 belongs to the SMAD

this gene exhibits very little sequence variation

differentiation and development

Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene

Mutation in this gene has been associated with familial hypertrophic cardiomyopathy

CD11A Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation Mothers against decapentaplegic homolog 2This gene encodes a member of the serine threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative