SSX Polyclonal Antibody, 20ul Hepatocytes interleukin 3 regulated encoded by

interleukin 3 regulated encoded by NFIL3 is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters

this protein is phosphorylated by the TGF-beta receptors

The encoded protein functions as a pre-mRNA splicing factor

The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits

The expression of this gene was detected in many normal tissues but not in most cancer cell lines

SSX Polyclonal Antibody, 20ul Hepatocytes interleukin 3 regulated encoded byThe product of SSX1 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine based immunotherapy. This gene, and also the SSX2 and SSX4 family members, have been involved in t(X; 18)(p11. ; q11. )