HES-6 Polyclonal Antibody, 50ul Gene Synthesis This protein possesses intrinsic kinase

This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals

which was initially cloned from human dermal papilla cells and is evolutionally conserved from drosophila through to humans

May be required for pre-mRNA splicing

this protein is likely involved in hair formation and spermatogenesis in human as well

disease:Chromosomal aberrations involving FOXO1 are a cause of rhabdomyosarcoma 2 (RMS2)

HES-6 Polyclonal Antibody, 50ul Gene Synthesis This protein possesses intrinsic kinaseHES6 encodes a member of a subfamily of basic helix loop helix transcription repressors that have homology to the Drosophila enhancer of split genes. Members of HES6 family regulate cell differentiation in numerous cell types. Transcription cofactor HES 6 encoded by HES6 functions as a cofactor, interacting with other transcription factors through a tetrapeptide domain in its C terminus. Alternatively spliced transcript variants encoding different