SRA1 Monoclonal Antibody, 100ul[BT-MCA1155] Aspirating Pipets This proto-oncogene plays a role

This proto-oncogene plays a role in the survival and proliferation of B lymphocytes

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50| a protein involved in DNA double-strand break repair

and is considered to be an oncogene

Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries

and SAM (sterile alpha motif) domains

SRA1 Monoclonal Antibody, 100ul[BT-MCA1155] Aspirating Pipets This proto-oncogene plays a roleBoth long non coding and protein coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non NR activities, including metabolism, adipogenesis and chromatin organization.