Dynactin 2 Polyclonal Antibody, 100ul Electronic Pipette Inhibits HSPA8/HSC70 ATPase and chaperone

Inhibits HSPA8/HSC70 ATPase and chaperone activities Diseases associated with HSPH1 include hepatitis d

HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN

Differential expression of this gene has been observed in different types of malignancies

The product of MED13 is proposed to form a sub-complex with MED12

subcellular location:Localization to the cytoplasm or to the cell membrane is developmentally and ontogenetically regulated

Dynactin 2 Polyclonal Antibody, 100ul Electronic Pipette Inhibits HSPA8/HSC70 ATPase and chaperoneDCTN2 encodes a 50 kD subunit of dynactin, a macromolecular complex consisting of 10 11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER to Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4 5 copies per