IκB-beta(Phospho Ser23) Polyclonal Antibody, 20ul Mechanical Pipette Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported

Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation| and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization

Seems to play a role as an inhibitor of apoptosis

LRP10 encodes a low density lipoprotein receptor family protein

This gene is a member of the roadblock dynein light chain family

IκB-beta(Phospho Ser23) Polyclonal Antibody, 20ul Mechanical Pipette Several alternatively spliced transcript variantsThe protein encoded by this gene belongs to the NF kappa B inhibitor family, which inhibit NF kappa B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF kappa B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been