DMRT2 Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy The serine/threonine-protein kinase tousled-like 2

The serine/threonine-protein kinase tousled-like 2 is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone

Two pseudogenes of this gene have been identified within this cluster on chromosome 7

Expression of this gene is induced by estrogen and altered in some breast cancers

It is required for pilus biogenesis

kb whose expression was highly restricted to circulating NK and T cells

DMRT2 Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy The serine/threonine-protein kinase tousled-like 2The protein encoded by this gene belongs to the DMRT gene family sharing a DM DNA binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3 genes involved in sex determination in these organisms. Also this gene is located in a region of the human genome (chromosome 9p24. 3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex determining gene(s) on chr 9.