Cortactin(Phospho Tyr421) Polyclonal Antibody, 20ul Centrifugal Filter including the heart

including the heart

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The encoded protein may be involved in cell survival and proliferation| and is associated with several disease states including cancer and Alzheimer's disease

The encoded protein was once thought to be a receptor for C1q

Belongs to the alkB family

Cortactin(Phospho Tyr421) Polyclonal Antibody, 20ul Centrifugal Filter including the heartThis gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase