CGL Polyclonal Antibody, 100ul Lysosome Involved in 2 distinct lysosomal

Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover

or fibronectin

A chromosomal aberration involving PRDM3 is found in a form of acute myeloid leukemia

It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin

An important paralog of this gene is MAP4K3

CGL Polyclonal Antibody, 100ul Lysosome Involved in 2 distinct lysosomalThis gene encodes a cytoplasmic enzyme in the trans sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms.