POT1 Polyclonal Antibody, 50ul Site-directed Mutagenesis The human HUNK gene localizes

The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome

The gene product interacts with certain inflammatory response factors| and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease

The precise function of this gene is unknown

which was reported to interact with 26S proteasome

a CGG-repeat expansion from 5-22 repeats to 68-450 repeats has been identified in the first intron of this gene

POT1 Polyclonal Antibody, 50ul Site-directed Mutagenesis The human HUNK gene localizesPOT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, protection of telomeres 1 functions as a member of a multi protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is