ANTR1 Polyclonal Antibody, 100ul Culture Tubes Defects in FLNA are a

Defects in FLNA are a cause of several syndromes

Mitogen-activated protein kinase 8 localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways

Among its related pathways are MAP Kinase Signaling andTGF-Beta Pathway

A pseudogene of this gene is found on chromosome 22

The protein encoded by this gene is an enzyme that catalyzes the oxidative conversion of delta-5-3-beta-hydroxysteroid precursors into delta-4-ketosteroids| which leads to the production of all classes of steroid hormones

ANTR1 Polyclonal Antibody, 100ul Culture Tubes Defects in FLNA are aThis gene encodes a type I transmembrane protein and is a tumor specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol