Histone H3 (Tri Methyl Lys79) Monoclonal Antibody(3G3), 50ul Glassware This nuclear protein interacts with

This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs

3 and an unprocessed pseudogene has been assigned to 16p12-p11

and that binding is enhanced when cytokeratins 8 and 18 are present

This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin

subcellular location:Concentrates at the leading edge of cells

Histone H3 (Tri Methyl Lys79) Monoclonal Antibody(3G3), 50ul Glassware This nuclear protein interacts withHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin