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TBX2 Polyclonal Antibody, 20ul Vortex Mixer Diseases associated with MYF5 include

SKU: 46690852609

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PLN111.00 PLN146.00

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TBX2 Polyclonal Antibody, 20ul Vortex Mixer Diseases associated with MYF5 includeTBX2 is a member of a phylogenetically conserved family of genes that share a common DNA binding domain, the T box. T box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent.

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Description

Diseases associated with MYF5 include skeletal muscle cancer and botryoid rhabdomyosarcoma

This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins

is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988)

acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs

3-glucuronyltransferase 1 encoded by B3GAT1 is a member of the glucuronyltransferase gene family

TBX2 Polyclonal Antibody, 20ul Vortex Mixer Diseases associated with MYF5 includeTBX2 is a member of a phylogenetically conserved family of genes that share a common DNA binding domain, the T box. T box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent.

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