NARF Polyclonal Antibody, 50ul In vitro Transcription Northern blot analysis shows that

Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas

Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals

2000 [PubMed: 11087666])

This gene encodes a protein with an N-terminal half that contains cysteine/histidine motifs and leucine zipper-like repeats

Genetic variation in this gene influences susceptibility to occlusive vascular disease

NARF Polyclonal Antibody, 50ul In vitro Transcription Northern blot analysis shows thatSeveral proteins have been found to be prenylated and methylated at their carboxyl terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A and B type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue