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HSP 90 (Acetyl Lys435) Polyclonal Antibody, 20ul Long RNA Synthesis Inhibits differentiation of CD34+ cell

SKU: 47747416827

4.9
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HSP 90 (Acetyl Lys435) Polyclonal Antibody, 20ul Long RNA Synthesis Inhibits differentiation of CD34+ cellThe protein encoded by HSP90AA1 is an inducible molecular chaperone that functions as a homodimer heat shock protein 90 alpha family class A member 1 aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co chaperones. Two transcript variants encoding different isoforms have been found for HSP90AA1.

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Description

Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro)

It has been suggested that defects in the human gene result in pipecolic acidemia

including Hirschsprung disease and some cancers

which maifests itself in a delayed and slow puberty

whose activity is required for cell cycle G1/S transition

HSP 90 (Acetyl Lys435) Polyclonal Antibody, 20ul Long RNA Synthesis Inhibits differentiation of CD34+ cellThe protein encoded by HSP90AA1 is an inducible molecular chaperone that functions as a homodimer heat shock protein 90 alpha family class A member 1 aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co chaperones. Two transcript variants encoding different isoforms have been found for HSP90AA1.

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