AHR Rabbit Polyclonal Antibody, 20ul Mammalian Expression This gene encodes a member

This gene encodes a member of the cytochrome P450 superfamily of enzymes

The protein encoded by SIX1 (SIX homeobox 1)is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product

The encoded protein has also been shown to transport anticancer drugs like bleomycin (PMID: 20037140) successful treatment has been correlated with the level of activity of this transporter in tumor cells

embryogenesis

Mutations in this gene may be associated with susceptibility to coronary artery disease

AHR Rabbit Polyclonal Antibody, 20ul Mammalian Expression This gene encodes a memberThe protein encoded by this gene is a ligand activated helix loop helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.