GCSc-Gamma Polyclonal Antibody, 20ul Reservoirs The two genes
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GCSc-Gamma Polyclonal Antibody, 20ul Reservoirs The two genesGlutamate cysteine ligase, also known as gamma glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC encodes Glutamate cysteine ligase catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22 p21. Mutations at GCLC have been associated with hemolytic anemia due to
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