POSTN Polyclonal Antibody, 100ul Pipette Micro Tips Three transcript variants encoding different

Three transcript variants encoding different isoforms have been found for CD83

A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E

Studies in mice suggest that this gene functions in wound healing and abdominal wall development

This protein is involved in cell adhesion

Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1

POSTN Polyclonal Antibody, 100ul Pipette Micro Tips Three transcript variants encoding differentThis gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects.