SEMA4A Polyclonal Antibody, 100ul Cell Separation and Collection PAGE3 is a member of

PAGE3 is a member of family of proteins that are expressed in a variety of tumors and in some fetal and reproductive tissues

This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain

Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes

The protein encoded by this gene is a member of the importin alpha family

it lacks peptidase activity

SEMA4A Polyclonal Antibody, 100ul Cell Separation and Collection PAGE3 is a member ofSEMA4A encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single pass type I membrane protein containing an immunoglobulin like C2 type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for