PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper |tissue specificity:Expressed at high levels

|tissue specificity:Expressed at high levels in heart| brain and skeletal muscle

This protein regulates the activity of many immediate-early genes

some of which encode the same protein

Members of this family have three conserved domains: an N-terminal homology domain

Negative regulator of ubiquitin like proteins 1 interacts with the product of the AIPL1 gene

PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper |tissue specificity:Expressed at high levelsPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.