Raf-1 Polyclonal Antibody, 20ul[BT-AP13537] Yeast Expression The catalytic portion of mitochondrial

The catalytic portion of mitochondrial ATP synthase consists of five different subunits (alpha| beta| gamma| delta| and epsilon) assembled with a stoichiometry of 3 alpha| 3 beta| and single representatives of the gamma| delta| and epsilon subunits

suggesting a link with Alzheimer disease

Alternatively spliced variants

This intronless gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain

Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized

Raf-1 Polyclonal Antibody, 20ul[BT-AP13537] Yeast Expression The catalytic portion of mitochondrialThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.