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Phospho-BRCA1 (S1423) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos The expression of TNFAIP2 was

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Phospho-BRCA1 (S1423) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos The expression of TNFAIP2 wasBRCA1 (BRCA1, DNA repair associated) encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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Description

The expression of TNFAIP2 was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein

and is thought to play a role in the early stage of recombinational repair of DNA

CGGBP1 (CGG triplet repeat binding protein 1) influences expression of the FMR1 gene (MIM 309550)

They physically associate with both proteasomes and ubiquitin ligases

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Phospho-BRCA1 (S1423) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos The expression of TNFAIP2 wasBRCA1 (BRCA1, DNA repair associated) encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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