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Porcine Scavenger Receptor Cysteine-rich Type 1 Protein M130, CD163 ELISA Kit, 96T Enzymes The beta subunit contains a

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Porcine Scavenger Receptor Cysteine-rich Type 1 Protein M130, CD163 ELISA Kit, 96T Enzymes The beta subunit contains aInvolved in clearance and endocytosis of hemoglobin haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin haptoglobin and subsequent breakdown of heme. Binds hemoglobin haptoglobin complexes in a calcium dependent and pH dependent manner. Induces a cascade of intracellular signals that involves tyrosine

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Description

The beta subunit contains a C-terminal domain which is involved in cell signaling

An important paralog of this gene is BARX2

preventing casein precipitation in milk

enzyme regulation:Activated by phosphorylation on Thr-174 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

Alternate splicing generates multiple transcript variants encoding distinct isoforms

Porcine Scavenger Receptor Cysteine-rich Type 1 Protein M130, CD163 ELISA Kit, 96T Enzymes The beta subunit contains aInvolved in clearance and endocytosis of hemoglobin haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin haptoglobin and subsequent breakdown of heme. Binds hemoglobin haptoglobin complexes in a calcium dependent and pH dependent manner. Induces a cascade of intracellular signals that involves tyrosine

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