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BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture Major structural component of the

SKU: 49318005994

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BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture Major structural component of theBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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Description

Major structural component of the ciliary rootlet

The protein may be involved in transduction of high-temperature heat responses in sensory ganglia

It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation

Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes

Diseases associated with GLB1L3 include leber congenital amaurosis

BRCA1 Polyclonal Antibody, 50ul[BT-AP00965] 3D Culture Major structural component of theBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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