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RBQ-3 Polyclonal Antibody, 100ul Cell Screening and Imaging There are three inhibitory families

SKU: 49886469484

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RBQ-3 Polyclonal Antibody, 100ul Cell Screening and Imaging There are three inhibitory familiesRBBP5 (RB binding protein 5, histone lysine methyltransferase complex subunit) encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A binding pocket B. Three alternatively spliced transcript variants

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Description

There are three inhibitory families in the superfamily| including the type 1 cystatins (stefins)| type 2 cystatins and the kininogens

This gene has multiple pseudogenes and is a member of the phosphatidylinositol glycan anchor biosynthesis gene family

The protein encoded by this gene is closely related to STAM| an adaptor protein involved in the downstream signaling of cytokine receptors| both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM)

and it may also be involved in some cases of cleft lip/palate

This gene encodes a member of the carboxylesterase large family

RBQ-3 Polyclonal Antibody, 100ul Cell Screening and Imaging There are three inhibitory familiesRBBP5 (RB binding protein 5, histone lysine methyltransferase complex subunit) encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A binding pocket B. Three alternatively spliced transcript variants

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