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Rb Polyclonal Antibody, 20ul[BT-AP07693] Pathway and Network Analysis AKR1C2 encodes a member of

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Rb Polyclonal Antibody, 20ul[BT-AP07693] Pathway and Network Analysis AKR1C2 encodes a member ofThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

AKR1C2 encodes a member of the aldo/keto reductase superfamily

There are two isoforms of PRPF38A that are produced as a result of alternative splicing events

HNRP proteins have also been identified outside of the nucleoplasm

Online Calibration: The MicroPette Plus can be calibrated online via the official website

As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors

Rb Polyclonal Antibody, 20ul[BT-AP07693] Pathway and Network Analysis AKR1C2 encodes a member ofThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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