Rb(Phospho Ser795) Polyclonal Antibody, 50ul Syringe Filter In tumor microenvironments

In tumor microenvironments

Additional alternatively spliced transcript variants of DYRK4 have been described

including RAB11B (RAB11B

Ras and Rab interactor 3 encoded by RIN3 is a member of the RIN family of Ras interaction-interference proteins

This protease also functions to process the precursor SUMO proteins into their mature form

Rb(Phospho Ser795) Polyclonal Antibody, 50ul Syringe Filter In tumor microenvironmentsThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.