ST2A1 Polyclonal Antibody, 50ul[BT-AP14510] Enzyme Activity Assays Expression of the human ortholog

Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells

together with SNAP25 (synaptosome-associated protein of 25 kDa)

The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system

Defects in this enzyme

it interacts with the three DNA-binding proteins of the shelterin complex

ST2A1 Polyclonal Antibody, 50ul[BT-AP14510] Enzyme Activity Assays Expression of the human orthologThis gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome.