Rock-1 Polyclonal Antibody, 50ul[BT-AP07968] Variant Libraries These enzymes are thought to

These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation

Pseudogenes of this gene are located on chromosomes 1

Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors

Opioid binding protein/cell adhesion molecule like is proteolytically processed to generate the mature protein

May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions

Rock-1 Polyclonal Antibody, 50ul[BT-AP07968] Variant Libraries These enzymes are thought toROCK1 encodes a protein serine threonine kinase that is activated when bound to the GTP bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP bound form and the active GTP bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor.