NF-κB p105 (Cleaved-Thr434) Rabbit Polyclonal Antibody, 50ul Stepper and modulation of DNA binding

and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription

and acts as a tumor suppressor in hepatoma cells

2000 [PubMed 10673339])

A pseudogene of this gene is located on the long arm of chromosome 3

and regulates the transcription of multiple genes including C-type natriuretic peptide

NF-κB p105 (Cleaved-Thr434) Rabbit Polyclonal Antibody, 50ul Stepper and modulation of DNA bindingGlycine rich region (GRR) appears to be a critical element in the generation of p50. The C terminus of p105 might be involved in cytoplasmic retention inhibition of DNA binding and transcription activation. NF kappa B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation immunity differentiation cell growth tumorigenesis and apoptosis. NF kappa B is a homo or