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OTOG Rabbit Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) This protein also localizes to

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OTOG Rabbit Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) This protein also localizes toThe protein encoded by this gene is a component of the acellular membranes of the inner ear. Disruption of the orthologous mouse gene shows that it plays a role in auditory and vestibular functions. It is involved in fibrillar network organization the anchoring of otoconial membranes and cupulae to the neuroepithelia and likely in sound stimulation resistance. Mutations in this gene cause autosomal recessive nonsyndromic deafness type 18B. Alternative

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Description

This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor

Defects in the gene encoding ARHGAP11A may cause mental retardation

Inhibitor of the caspase-activated DNase (DFF40)

T-cell receptor enhancers and GM-CSF promoters

PcG family members form multimeric protein complexes| which are involved in maintaining the transcriptional repressive state of genes over successive cell generations

OTOG Rabbit Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) This protein also localizes toThe protein encoded by this gene is a component of the acellular membranes of the inner ear. Disruption of the orthologous mouse gene shows that it plays a role in auditory and vestibular functions. It is involved in fibrillar network organization the anchoring of otoconial membranes and cupulae to the neuroepithelia and likely in sound stimulation resistance. Mutations in this gene cause autosomal recessive nonsyndromic deafness type 18B. Alternative

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