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Rb Polyclonal Antibody, 50ul[BT-AP07691] Vector Construction axon growth and regeneration

SKU: 50955411655

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EUR185.00 EUR220.00

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Rb Polyclonal Antibody, 50ul[BT-AP07691] Vector Construction axon growth and regenerationThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

axon growth and regeneration

The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes

Several alternatively spliced transcript variants

Mice that lac

This gene encodes a protein with six coiled-coil domains

Rb Polyclonal Antibody, 50ul[BT-AP07691] Vector Construction axon growth and regenerationThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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