GRK 4 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) |Type IV collagen is the

|Type IV collagen is the major structural component of glomerular basement membranes (GBM)| forming a 'chicken-wire' meshwork together with laminins| proteoglycans and entactin/nidogen

and a C-terminal region containing multiple XFXFG repeats

The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins

a member of the CC-chemokine family

In response to BMP ligands| this protein can be phosphorylated and activated by the BMP receptor kinase

GRK 4 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) |Type IV collagen is theGRK4 encodes a member of the guanine nucleotide binding protein (G protein) coupled receptor kinase subfamily of the Ser Thr protein kinase family. The protein phosphorylates the activated forms of G protein coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene.