Raf-1(Phospho Thr269) Polyclonal Antibody, 100ul Mammalian Expression adrenocorticotrophin| essential for normal steroidogenesis

adrenocorticotrophin| essential for normal steroidogenesis and the maintenance of normal adrenal weight| and lipotropin beta are the major end products

Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders

CLIP2 is hemizygously deleted in Williams syndrome

An important paralog of this gene is ERAP2

HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts

Raf-1(Phospho Thr269) Polyclonal Antibody, 100ul Mammalian Expression adrenocorticotrophin| essential for normal steroidogenesisThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.