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GLI2 Polyclonal Antibody, 100ul In vitro Assessment The type 2 cystatin proteins

SKU: 51498518932

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GLI2 Polyclonal Antibody, 100ul In vitro Assessment The type 2 cystatin proteinsThis gene encodes a protein which belongs to the C2H2 type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene

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Description

The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions| where they appear to provide protective functions

which is important for the microbicidal activity of these cells

This gene encodes the protein elongin C

Overexpression of this gene may play a role in leukemogenesis| and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein

This protein may tightly associate or interact with the pyruvate dehydrogenase complex

GLI2 Polyclonal Antibody, 100ul In vitro Assessment The type 2 cystatin proteinsThis gene encodes a protein which belongs to the C2H2 type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene

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