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Septin 1 Polyclonal Antibody, 100ul Capsule Filter This protein is expressed in

SKU: 51660710576

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Septin 1 Polyclonal Antibody, 100ul Capsule Filter This protein is expressed inSEPT1 is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. SEPT1 encodes Septin 1 that can form homo and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full length nature of these variants has not been determined.

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Description

This protein is expressed in lymphoid tissues

Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas

it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression

it is possible that this gene plays an important role in the development of the cochlea and vestibulum

This gene encodes a protein with similarity to members of the myosin light chain kinase family

Septin 1 Polyclonal Antibody, 100ul Capsule Filter This protein is expressed inSEPT1 is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. SEPT1 encodes Septin 1 that can form homo and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full length nature of these variants has not been determined.

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