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HCF1 Polyclonal Antibody, 20ul Pathway and Network Analysis Activation of this gene may

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HCF1 Polyclonal Antibody, 20ul Pathway and Network Analysis Activation of this gene mayHCFC1 is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N terminal chain and the corresponding C terminal chain. The final form of this protein consists of noncovalently bound N and C terminal

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Description

Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix

and colon carcinomas

Dok-4 (Downstream of kinase-4) is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins

which is required for transcriptional activation of genes normally repressed by chromatin

which are derived from a single precursor protein

HCF1 Polyclonal Antibody, 20ul Pathway and Network Analysis Activation of this gene mayHCFC1 is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N terminal chain and the corresponding C terminal chain. The final form of this protein consists of noncovalently bound N and C terminal

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